Andreas Gisel has a degree in Biology from the Swiss Federel Institute of Technology, Zurich, Switzerland and got his PhD in Biochemistry and Molecular Biology from the same Institute in the department of Plant Sciences under Prof. Ingo Potrykus. He spent four years as post-doctoral fellow at the University of California Berkeley working on macromolecular trafficking in plants and on virus induced gene silencing. Back in Switzerland he continued his work on virus induced gene silencing and the role of small RNA at the Friedrich Miescher Institute in Basel, an Institute of the Novartis Foundation. During this time Andreas Gisel started to work also as bioinformatician. Since then Andreas Gisel had positions as bioinformatician at the pharmaceutical company Novartis SA and at the Italian National Research Council.
Andreas Gisel is an Executive Board member of the global bioinformatics network ‘EMBnet’ and acted in several occasions all over the world as trainer in basic and advanced bioinformatics.
His interest of research is the development of sequence analysis tools for sequence data produced by the next generation sequencing technologies with specialization on non-coding RNA, methylation profiles and genotyping by sequencing. He is very much interested to interact, with his molecular biology background, with researcher interested in using NGS technology for there research and advise them how to plan the experiments to get most out of it. He also offers to collaborate in biological projects as a data analysis specialist so that the data from NGS approaches such as RNA-seq, smallRNA-seq, BS-seq and GBS have the best interpretation using open access tools and in-house developed tools and algorithms.
Selected publications:
Data integration in the era of omics: current and future challenges. David Gomez-Cabrero, Imad Abugessaisa, Dieter Maier, Andrew Teschendorff, Matthias Merkenschlager, Andreas Gisel, Esteban Ballestar, Erik Bongcam-Rudloff, Ana Conesa, Jesper Tegnér BMC Systems Biology 2014, 8(Suppl 2):I1
Small RNAs containing the pathogenic determinant of a chloroplast-replicating viroid guide degradation of a host mRNA as predicted by RNA silencing. Navarro, A Gisel, A Rodio, ME Degado, S Flores, R Di Serio, F Plant J Feb 14 2012
Concepts, Historical Milestones and the Central Place of Bioinformatics in Modern Biology: A European Perspective. Attwood, T.K Gisel, A Eriksson, N-E and Bongcam-Rudloff, E Bioinformatics, edited by: Dr. Mahmood Akhavan Mahdavi, INTECH ISBN 978-953-307-282-1
Citrus tristeza virus infection induces the accumulation of viral small RNAs (21- 24-nt) mapping preferentially at the 3′-terminal region of the genomic RNA and affects the host small RNA profile. Ruiz-Ruiz S, Navarro B, Gisel A, Peña L, Navarro L, Moreno P, Di Serio F, Flores R Plant Mol Biol. 2011 Feb 15
Deep sequencing of viroid-derived small RNAs from grapevine provides new insights on the role of RNA silencing in plant-viroid interaction. Navarro B, Pantaleo V, Gisel A, Moxon S, Dalmay T, Bisztray G, Di Serio F, Burgyán J. PLoS One. 2009 Nov 5;4(11):e7686.
Deep sequencing of the small RNAs derived from two symptomatic variants of a chloroplastic viroid: implications for their genesis and for pathogenesis. Di Serio F, Gisel A, Navarro B, Delgado S, Martínez de Alba AE, Donvito G, Flores R. PLoS One. 2009 Oct 21;4(10):e7539.
